AngioPlate™384

Name: AngioPlate™384
SKU: A002; A002-2; A002-3
Availability: InStock

$1,030.00 CAD

AngioPlate is an organ on a chip platform designed to replicate the complex structure and function of human tissues. Each AngioPlate contains 128 independent tissue culture units, making it the highest throughput system available in the market, and is compatible with automation workflows. Each unit contains a inlet, middle, and outlet well connected together via two channels. The middle well contains a 3D printed sacrificial template that can be encapsulated by a natural hydrogel. Upon dissolving the templates, the system produces a perfusable structure within the hydrogel matrix, which can then be populated with cells. The absence of membranes between the perfusable structure and surrounding matrix enables direct interactions between cells to mimick physiological tissue environments.

SKU: A002; A002-2; A002-3 Category: Platform

Description
Specifications

This versatile platform supports the creation of various tissue models, including tubular blood vessels, bifurcating vascular networks, renal epithelial tubules, colon tubes, and vascularized spheroids or organoids. These models can be used to study tissue barrier disruption, immune response, fibrosis and more in a highly controlled environment. With customizable designs, including three standard templates and the option for tailored configurations, AngioPlate offers unparalleled flexibility for diverse research needs. Bidirectional perfusion of tissues is achieved using the IFlowRocker, eliminating the need for pumps. For unidirectional perfusion, researchers can explore the UniPlate384 system. AngioPlate is compatible with the AngioTEER sensor, enabling realtime, continuous monitoring of tissue barrier integrity across 128 tissue units in a plate. The openwell design ensures easy access for pipetting and tissue removal for downstream analysis, while the optically clear plate bottom supports highcontent imaging using confocal microscopy and highthroughput analysis with plate readers. The 384well design also minimizes the use of cells and reagents to significantly reduce experimental costs per data point. To learn more, please visit www.organo-biotech.com/posters.

For non-commercial research use only.
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This product is also available on Cedarlane

Specifications

Product Code	A002; A002-2; A002-3
Number of Cultures per Plate	128
Sterilization Method	UV sterilized
Storage Condition	Room temperature (15-25 °C)
Storage Time	3 Months
Plate Format	SBS standard 384 well plate
Materials	– Top plate: virgin polystyrene. – Bottom plate: optical quality, low compound-absorbing plastic – Internal sacrificial template: proprietary polymers
Perfusion	Gravity driven perfusion with IFlowRocker (B001)
Applications	Perfused 3D tissue and organoid culture
Readouts	– Sensor (TEER with AngioTEER, B002); – Imaging (phase contrast, widefield fluorescence, confocal); – Plate reader (absorption, fluorescence, luminescence); – Off plate (Histology, ELISA, RNA/DNA analysis, MS, biochemistry)