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UniPlate™384
$1,160.00 CAD
UniPlate is an organ on a chip platform designed to replicate the complex structure and function of human tissues under uni directional media perfusion. Each UniPlate contains 64 independent tissue culture units, and is compatible with automation workflows. Each unit contains an inlet, middle, and outlet well connected together via two channels as well as a slanted ramp for media recirculation. The middle well contains a 3D printed sacrificial template that can be encapsulated by a natural hydrogel. Upon dissolving the templates, the system produces a perfusable structure within the hydrogel matrix, which can then be populated with cells. The absence of membranes between the perfusable structure and surrounding matrix enables direct interactions between cells to mimick physiological tissue environments.
This versatile platform supports the creation of various tissue models, including tubular blood vessels, bifurcating vascular networks, renal epithelial tubules, colon tubes, and vascularized spheroids or organoids. These models can be used to study tissue barrier disruption, immune response, fibrosis, and more in a highly controlled environment. With customizable designs, including three standard templates and the option for tailored configurations, the UniPlate™384 offers unparalleled flexibility for diverse research needs. The UniPlate is specially designed to provide gravity driven unidirectional perfusion of tissues when used in combination with the IFlowRocker, eliminating the need for pumps. The UniPlate™384 is also compatible with the AngioTEER sensor, enabling real time, continuous monitoring of tissue barrier integrity across 64 tissue units in a plate. The open well design ensures easy access for pipetting and tissue removal for downstream analysis, while the optically clear plate bottom supports high content imaging using confocal microscopy and high throughput analysis with plate readers. The 384 well design minimizes the use of cells and reagents, significantly reducing experimental costs per data point. To learn more, please visit www.organo-biotech.com/posters.
- For non-commercial research use only.
- We ship worldwide. Shipping costs by FedEx will be added during checkout.
- All prices mentioned are in Canadian Dollars.
- Click here to see the terms & agreements. By placing the order, you accept our terms and conditions.
- View the product specification
- This product is also available on Cedarlane
Specifications
| Product Code | A003; A003-2; A003-3 |
|---|---|
| Number of Cultures per Plate | 64 |
| Sterilization Method | UV sterilized |
| Storage Condition | Room temperature (15-25 °C) |
| Storage Time | 3 Months |
| Plate Format | SBS standard 384 well plate |
| Materials | – Top plate: virgin polystyrene |
| Perfusion | Gravity-driven perfusion with IFlowRocker (B001) |
| Applications | Perfused 3D tissue and organoid culture |
| Readouts | – Sensor: TEER with AngioTEER (B002) |
Key Features
64 tissue culture units
Pump-free uni-directional perfusion
Long-term recirculation of immune cells
Membrane-free 3D tissue culture in hydrogel matrix
Customizable tissue architecture
Automation compatible
